Cellulose 2,3-Di(p-chlorophenylcarbamate) Bonded to Silica Gel for Resolution of Enantiomers

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	Cellulose 2,3-Di(p-chlorophenylcarbamate) Bonded to Silica Gel for Resolution of Enantiomers
	Peng, Gui Ming 1,2; Wu, Su Qin 1; Zhang, Wei Guang 1; Fan, Jun 1; Zheng, Sheng Run 1; Xu, Gang 2; Xu, Xue Qing 2
	2013-06-01
发表期刊	ANALYTICAL SCIENCES
卷号	29 期号:6 页码:637-642
摘要	In this study, 6-azido-2,3-di(p-chlorophenylcarbamoylated) cellulose was synthesized and bonded onto aminized silica gel to obtain a new chiral stationary phase. Enantioselectivity of the chiral stationary phase and Chiralcel OF suggested promising chiral separation ability of the new cellulose chiral stationary phase. In addition, the effect of trifluoroacetic acid, diethylamine on enantioselectivity and retention factors on the chiral stationary phase in high performance liquid chromatography was investigated. Experimental results revealed that resolution increased as the trifluoroacetic acid concentration increased to 0.3% while resolution declined as the diethylamine concentration increased. Therefore, the optimal concentrations of trifluoroacetic acid and diethylamine were determined to be 0.3 and 0.1%, respectively. In most cases, trifluoroacetic acid shortened the retention of the first eluted enantiomer while it increased the retention of the other. For acidic compounds, with the existence of diethylamine in the mobile phase, the retention of both enantiomers decreased. But for basic compounds, the retention of both enantiomers increased.
文章类型	Article
WOS标题词	Science & Technology ; Physical Sciences
研究领域[WOS]	Chemistry
关键词[WOS]	CHIRAL STATIONARY PHASES ; LIQUID-CHROMATOGRAPHY ; TRIPHENYLCARBAMATE DERIVATIVES ; PHENYLALANINE ANALOGS ; ACIDIC ADDITIVES ; PERFORMANCE ; ENANTIOSEPARATION ; RECOGNITION ; SYSTEM ; AMINES
收录类别	SCI
语种	英语
WOS类目	Chemistry, Analytical
WOS记录号	WOS:000320900700007
引用统计	被引频次：4[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.giec.ac.cn/handle/344007/9144
专题	中国科学院广州能源研究所
作者单位	1.S China Normal Univ, Sch Chem & Environm, Guangzhou 510006, Guangdong, Peoples R China 2.Chinese Acad Sci, Guangzhou Inst Energy Convers, Key Lab Renewable Energy & Gas Hydrate, Guangzhou 510640, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Peng, Gui Ming,Wu, Su Qin,Zhang, Wei Guang,et al. Cellulose 2,3-Di(p-chlorophenylcarbamate) Bonded to Silica Gel for Resolution of Enantiomers[J]. ANALYTICAL SCIENCES,2013,29(6):637-642.
APA	Peng, Gui Ming.,Wu, Su Qin.,Zhang, Wei Guang.,Fan, Jun.,Zheng, Sheng Run.,...&Xu, Xue Qing.(2013).Cellulose 2,3-Di(p-chlorophenylcarbamate) Bonded to Silica Gel for Resolution of Enantiomers.ANALYTICAL SCIENCES,29(6),637-642.
MLA	Peng, Gui Ming,et al."Cellulose 2,3-Di(p-chlorophenylcarbamate) Bonded to Silica Gel for Resolution of Enantiomers".ANALYTICAL SCIENCES 29.6(2013):637-642.