Extraction of flavonoids from Glycyrrhiza residues using deep eutectic solvents and its molecular mechanism

doi:10.1016/j.molliq.2022.119848

GIEC OpenIR

	Extraction of flavonoids from Glycyrrhiza residues using deep eutectic solvents and its molecular mechanism
	Yu, Qiang 1; Wang, Fan 2,3; Jian, Yating 2,4; Chernyshev, Victor M.5; Zhang, Yu2 ; Wang, Zhongming2 ; Yuan, Zhenhong2 ; Chen, Xiaoyan 2
	2022-10-01
发表期刊	JOURNAL OF MOLECULAR LIQUIDS
ISSN	0167-7322
卷号	363 页码:11
通讯作者	Yu, Qiang(yuqiang@scau.edu.cn) ; Chen, Xiaoyan(chenxy@ms.giec.ac.cn)
摘要	The re-extraction of bioactive compounds from Chinese herb residues is significant for the maximum uti-lization of biomass resources. However, conventional alcoholic and aqueous solvents are unsuitable for recovering those compounds. In this study, 14 deep eutectic solvents (DESs) were used to improve the efficiency of flavonoid extraction from Glycyrrhiza residues. The maximal total extraction rate (10.68 mg/g) for four flavonoids (liquiritin, isoliquiritin, liquiritigenin, and isoliquiritigenin) was achieved using choline chloride-glycolic acid as the DES under optimal conditions. The extraction rate was 83.03 % higher than that by 60 % ethanol, a traditional solvent. Analysis of the associated molecular mechanism based on density functional theory showed that interactions between the solvent and liquiritin were dominated by hydrogen bonds followed by Van der Waals forces, whereas the bonding between the sol-vent and liquiritigenin only involved Van der Waals forces, thereby verifying the significance of the strength of hydrogen bonding in the DES-flavonoid extraction process.
关键词	Deepeutecticsolvent Densityfunctionaltheory Flavonoidextraction Glycyrrhizaresidue Molecularmechanism
DOI	10.1016/j.molliq.2022.119848
关键词[WOS]	TRADITIONAL CHINESE MEDICINE ; GREEN EXTRACTION ; IONIC-LIQUID ; EFFICIENT EXTRACTION ; BIOACTIVE COMPOUNDS ; DYNAMICS ; MEDIA
收录类别	SCI
语种	英语
资助项目	National Key R&D Program of China[2019YFC1906602] ; National Natural Science Foundation of China[51876206] ; Science and Technology Program of Guangzhou[202103000011]
WOS研究方向	Chemistry ; Physics
项目资助者	National Key R&D Program of China ; National Natural Science Foundation of China ; Science and Technology Program of Guangzhou
WOS类目	Chemistry, Physical ; Physics, Atomic, Molecular & Chemical
WOS记录号	WOS:000831781400010
出版者	ELSEVIER
引用统计	被引频次：19[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.giec.ac.cn/handle/344007/37011
专题	中国科学院广州能源研究所
通讯作者	Yu, Qiang; Chen, Xiaoyan
作者单位	1.South China Agr Univ, Inst Biomass Engn, Guangdong Engn Technol Res Ctr Agr & Forestry Biom, Key Lab Energy Plants Resource & Utilizat,Minist A, Guangzhou 510642, Peoples R China 2.Chinese Acad Sci, Guangzhou Inst Energy Convers, CAS Key Lab Renewable Energy, Guangdong Prov Key Lab New & Renewable Energy Res, Guangzhou 510640, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100039, Peoples R China 4.Univ Sci & Technol China, Sch Energy Sci & Engn, Hefei 230026, Peoples R China 5.Platov South Russian State Polytech Univ NPI, Novocherkassk 346428, Russia
推荐引用方式 GB/T 7714	Yu, Qiang,Wang, Fan,Jian, Yating,et al. Extraction of flavonoids from Glycyrrhiza residues using deep eutectic solvents and its molecular mechanism[J]. JOURNAL OF MOLECULAR LIQUIDS,2022,363:11.
APA	Yu, Qiang.,Wang, Fan.,Jian, Yating.,Chernyshev, Victor M..,Zhang, Yu.,...&Chen, Xiaoyan.(2022).Extraction of flavonoids from Glycyrrhiza residues using deep eutectic solvents and its molecular mechanism.JOURNAL OF MOLECULAR LIQUIDS,363,11.
MLA	Yu, Qiang,et al."Extraction of flavonoids from Glycyrrhiza residues using deep eutectic solvents and its molecular mechanism".JOURNAL OF MOLECULAR LIQUIDS 363(2022):11.