Chemoenzymatic conversion of furfural to methyl-2-furotate

doi:10.1002/bbb.2301

GIEC OpenIR

	Chemoenzymatic conversion of furfural to methyl-2-furotate
	Song, Miaojia 1,2; Lu, Jianping 1,2; Zhang, Yu1 ; Sun, Yongming1 ; Yuan, Zhenhong1 ; Wang, Zhongming1
	2021-10-18
发表期刊	BIOFUELS BIOPRODUCTS & BIOREFINING-BIOFPR
ISSN	1932-104X
页码	11
通讯作者	Zhang, Yu(zhangyu@ms.giec.ac.cn)
摘要	Furfural (FF) is an important bio-based platform compound derived from lignocellulose. It can be converted into many industrially valuable chemicals, a typical one being methyl-2-furoate (MF). At present, MF production depends largely on vigorous one-step chemical catalysis (oxidative esterification), in which expensive catalysts (precious metals) and a high temperature (60-120 degrees C) are required. To reduce the costs of this procedure, a mild, green, and cheap chemoenzymatic process is proposed where FF is initially chemically oxidized to furoic acid (FA), and then FA is enzymatically esterified to MF. Neither step requires an expensive catalyst, and both occur at low temperatures (30-50 degrees C). For the chemical oxidation process, the optimized FA yield of 83.7% was obtained at 40 degrees C with an FF/BTIC (1,3-bis(2,4,6-trimethylphenyl) imidazolium chloride) molar ratio of 0.18, 10 mL N-methyl pyrrolidone, and 0.1 MPa oxygen pressure. For the enzymatic esterification, the optimized MF yield reached 80.6% at 50 degrees C with 50 mg center dot mL(-1) enzyme loading and an alcohol/acid ratio of 7:1. Kinetic studies demonstrated the oxidation to be a sixth-order reaction, and the esterification to be an endothermic reaction. For both oxidation and esterification reactions, the relationship between the rate constant and temperature agreed well with the Arrhenius equation. For esterification, the relationship between the equilibrium constant and the temperature also agreed with the Van't Hoff equation. A 67.5% MF yield was obtained when sequential oxidation and esterification were initiated from FF. The development of chemoenzymatic processes for MF production from FF is effective and has potential value in decreasing the production cost of MF. (c) 2021 Society of Chemical Industry and John Wiley & Sons, Ltd
关键词	biorefinery chemoenzymatic furfural methyl-2-furoate kinetics
DOI	10.1002/bbb.2301
关键词[WOS]	SELECTIVE OXIDATIVE ESTERIFICATION ; N-HETEROCYCLIC CARBENE ; ALIPHATIC-ALCOHOLS ; FUROIC ACID ; BIOMASS ; CATALYSTS ; HMF ; CHEMICALS ; PLATFORM ; PRETREATMENT
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[21978288] ; National Key Research and Development Project of China[2018YFB1501701] ; National Key Research and Development Project of China[2019YFC1906602]
WOS研究方向	Biotechnology & Applied Microbiology ; Energy & Fuels
项目资助者	National Natural Science Foundation of China ; National Key Research and Development Project of China
WOS类目	Biotechnology & Applied Microbiology ; Energy & Fuels
WOS记录号	WOS:000708059200001
出版者	WILEY
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.giec.ac.cn/handle/344007/35054
专题	中国科学院广州能源研究所
通讯作者	Zhang, Yu
作者单位	1.Chinese Acad Sci, Guangzhou Inst Energy Convers, Guangzhou 510640, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China
第一作者单位	中国科学院广州能源研究所
推荐引用方式 GB/T 7714	Song, Miaojia,Lu, Jianping,Zhang, Yu,et al. Chemoenzymatic conversion of furfural to methyl-2-furotate[J]. BIOFUELS BIOPRODUCTS & BIOREFINING-BIOFPR,2021:11.
APA	Song, Miaojia,Lu, Jianping,Zhang, Yu,Sun, Yongming,Yuan, Zhenhong,&Wang, Zhongming.(2021).Chemoenzymatic conversion of furfural to methyl-2-furotate.BIOFUELS BIOPRODUCTS & BIOREFINING-BIOFPR,11.
MLA	Song, Miaojia,et al."Chemoenzymatic conversion of furfural to methyl-2-furotate".BIOFUELS BIOPRODUCTS & BIOREFINING-BIOFPR (2021):11.