Insights into removal of sulfonamides in anaerobic activated sludge system: Mechanisms, degradation pathways and stress responses

doi:10.1016/j.jhazmat.2021.127248

GIEC OpenIR

	Insights into removal of sulfonamides in anaerobic activated sludge system: Mechanisms, degradation pathways and stress responses
	Zhao, Qi 1; Guo, Wanqian 1; Luo, Haichao 1; Xing, Chuanming 1; Wang, Huazhe 1; Liu, Banghai 1; Si, Qishi 1; Li, Denian 2; Sun, Lushi 3; Ren, Nanqi 1
	2022-02-05
发表期刊	JOURNAL OF HAZARDOUS MATERIALS
ISSN	0304-3894
卷号	423 页码:12
通讯作者	Guo, Wanqian(gouwanqian@hit.edu.cn)
摘要	The fate of antibiotics in activated sludge has attracted increasing interests. However, the focus needs to shift from concerning removal efficiencies to understanding mechanisms and sludge responding to antibiotic toxicity. Herein, we operated two anaerobic sequencing batch reactors (ASBRs) for 200 days with sulfadiazine (SDZ) and sulfamethoxazole (SMX) added. The removal efficiency of SMX was higher than that of SDZ. SDZ was removed via adsorption (9.91-21.18%) and biodegradation (10.20-16.00%), while biodegradation (65.44-86.26%) was dominant for SMX removal. The mechanisms involved in adsorption and biodegradation were investigated, including adsorption strength, adsorption sites and the roles of enzymes. Protein-like substance (tryptophan) functioned vitally in adsorption by forming complexes with sulfonamides. P450 enzymes may catalyze sulfonamides degradation via hydroxylation and desulfurization. Activated sludge showed distinct responses to different sulfonamides, reflected in the changes of microbial communities and functions. These responses were related to sulfonamides removal, corresponding to the stronger adsorption capacity of activated sludge in ASBRSDZ and degradation capacity in ASBR-SMX. Furthermore, the reasons for different removal efficiencies of sulfonamides were analyzed according to steric and electronic effects. These findings propose insights into antibiotic removal and broaden the knowledge for self-protection mechanisms of activated sludge under chronic toxicities of antibiotics.
关键词	Antibiotics Stress responses Biodegradation Enzymes Biotransformation products
DOI	10.1016/j.jhazmat.2021.127248
关键词[WOS]	EXTRACELLULAR POLYMERIC SUBSTANCES ; MICROBIAL COMMUNITY ; WASTE-WATER ; ELECTRON-TRANSFER ; SERUM-ALBUMIN ; ANTIBIOTICS ; SULFAMETHOXAZOLE ; BIODEGRADATION ; SORPTION ; PHARMACEUTICALS
收录类别	SCI
语种	英语
资助项目	National Key R&D Pro-gram of China[2019YFC19066] ; National Natural Science Foundation of China[51978201] ; State Key Laboratory of Urban Water Resource and Environment[2020DX08]
WOS研究方向	Engineering ; Environmental Sciences & Ecology
项目资助者	National Key R&D Pro-gram of China ; National Natural Science Foundation of China ; State Key Laboratory of Urban Water Resource and Environment
WOS类目	Engineering, Environmental ; Environmental Sciences
WOS记录号	WOS:000704630800005
出版者	ELSEVIER
引用统计	被引频次：31[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.giec.ac.cn/handle/344007/35045
专题	中国科学院广州能源研究所
通讯作者	Guo, Wanqian
作者单位	1.Harbin Inst Technol, State Key Lab Urban Water Resource & Environm, Harbin, Peoples R China 2.Chinese Acad Sci, Guangzhou Inst Energy Convers, Lab Integrated Technol Urban & Rural Mines Exploi, 2 Nengyuan Rd, Guangzhou 510640, Guangdong, Peoples R China 3.Huazhong Univ Sci & Technol, Sch Energy & Power Engn, State Key Lab Coal Combust, Wuhan 430074, Peoples R China
推荐引用方式 GB/T 7714	Zhao, Qi,Guo, Wanqian,Luo, Haichao,et al. Insights into removal of sulfonamides in anaerobic activated sludge system: Mechanisms, degradation pathways and stress responses[J]. JOURNAL OF HAZARDOUS MATERIALS,2022,423:12.
APA	Zhao, Qi.,Guo, Wanqian.,Luo, Haichao.,Xing, Chuanming.,Wang, Huazhe.,...&Ren, Nanqi.(2022).Insights into removal of sulfonamides in anaerobic activated sludge system: Mechanisms, degradation pathways and stress responses.JOURNAL OF HAZARDOUS MATERIALS,423,12.
MLA	Zhao, Qi,et al."Insights into removal of sulfonamides in anaerobic activated sludge system: Mechanisms, degradation pathways and stress responses".JOURNAL OF HAZARDOUS MATERIALS 423(2022):12.