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Antisense knockdown of pyruvate dehydrogenase kinase promotes the neutral lipid accumulation in the diatom Phaeodactylum tricornutum
Ma, Yu-Han1; Wang, Xiang1; Niu, Ying-Fang1; Yang, Zhi-Kai1; Zhang, Meng-Han1; Wang, Zhong-Ming2; Yang, Wei-Dong1; Liu, Jie-Sheng1; Li, Hong-Ye1
2014-08-09
Source PublicationMICROBIAL CELL FACTORIES
Volume13
AbstractBackground: Microalgae have been an emerging biofuel resource; however, the germplasm improvement has been slow due to the lack of molecular tools. Pyruvate dehydrogenase kinase (PDK) deactivates the pyruvate dehydrogenase complex (PDC) which catalyzes the oxidative decarboxylation of pyruvate. Acetyl-CoA production via PDC is important in plant tissues that are active in fatty acid synthesis.
SubtypeArticle
KeywordMicroalga Pyruvate Dehydrogenase Kinase Antisense Lipid Biofuel
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
DOI10.1186/s12934-014-0100-9
WOS Subject ExtendedBiotechnology & Applied Microbiology
WOS KeywordARABIDOPSIS-THALIANA ; FLOW-CYTOMETRY ; THALASSIOSIRA-PSEUDONANA ; BRASSICA-NAPUS ; MECHANISMS ; METABOLISM ; EXTRACTION ; ACID ; GENE ; COA
Indexed BySCI
Language英语
WOS SubjectBiotechnology & Applied Microbiology
WOS IDWOS:000340802800001
Citation statistics
Cited Times:28[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.giec.ac.cn/handle/344007/10627
Collection中国科学院广州能源研究所
Affiliation1.Jinan Univ, Guangdong Higher Educ Inst, Key Lab Eutrophicat & Red Tide Prevent, Guangzhou 510632, Guangdong, Peoples R China
2.Chinese Acad Sci, Guangzhou Inst Energy Convers, Guangzhou 510650, Guangdong, Peoples R China
Recommended Citation
GB/T 7714
Ma, Yu-Han,Wang, Xiang,Niu, Ying-Fang,et al. Antisense knockdown of pyruvate dehydrogenase kinase promotes the neutral lipid accumulation in the diatom Phaeodactylum tricornutum[J]. MICROBIAL CELL FACTORIES,2014,13.
APA Ma, Yu-Han.,Wang, Xiang.,Niu, Ying-Fang.,Yang, Zhi-Kai.,Zhang, Meng-Han.,...&Li, Hong-Ye.(2014).Antisense knockdown of pyruvate dehydrogenase kinase promotes the neutral lipid accumulation in the diatom Phaeodactylum tricornutum.MICROBIAL CELL FACTORIES,13.
MLA Ma, Yu-Han,et al."Antisense knockdown of pyruvate dehydrogenase kinase promotes the neutral lipid accumulation in the diatom Phaeodactylum tricornutum".MICROBIAL CELL FACTORIES 13(2014).
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