Effects of Alcohol Compounds on the Growth and Lipid Accumulation of Oleaginous Yeast Trichosporon fermentans

doi:10.1371/journal.pone.0046975

GIEC OpenIR > 中国科学院广州能源研究所

	Effects of Alcohol Compounds on the Growth and Lipid Accumulation of Oleaginous Yeast Trichosporon fermentans
	Huang, Chao 1,2; Wu, Hong 1; Liu, Li-ping 3; Lou, Wen-yong 3; Zong, Min-hua 1
	2012-10-05
发表期刊	PLOS ONE
卷号	7 期号:10
摘要	The inhibitors present in dilute acid-treated lignocellulosic hydrolysates would show great effect on the growth and product formation of microorganisms. To understand their inhibitory law and mechanism on oleaginous microorganism could help improving the efficiency of lignocellulose hydrolysis, detoxification, and lipid fermentation. The effects of four representative alcohol compounds present in lignocellulosic hydrolysates, including furfuryl alcohol, vanillyl alcohol, catechol, hydroquinone on the cell growth and lipid accumulation of Trichosporon fermentans were systematically investigated in this work. The toxicity of selected alcohol compounds was well related to their log P value except furfuryl alcohol, whose log P value was the minimum but with the highest toxicity to T. fermentans. The inhibition of all the alcohol compounds on the growth of T. fermentans was more serious than on the lipid synthesis. Also, the growth of T. fermentans was more sensitive to the variation of inoculum size, temperature, and initial pH than lipid synthesis in the presence of alcohol compounds. Initial pH had more profound influence on the lipid fermentation than inoculum size and cultural temperature did. Careful control of fermentation conditions could be helpful for improving lipid yield of T. fermentans in lignocellulosic hydrolysates. Among the four alcohol compounds tested, most alcohol compounds showed inhibition on both sugar consumption and malic enzyme activity of T. fermentans. However, vanillyl alcohol had little influence on the malic enzyme activity. Similarly, all alcohol compounds except vanillyl alcohol exerted damage on the cell membrane of T. fermentans.
文章类型	Article
WOS标题词	Science & Technology
DOI	10.1371/journal.pone.0046975
研究领域[WOS]	Science & Technology - Other Topics
关键词[WOS]	ETHANOLOGENIC ESCHERICHIA-COLI ; CELL OIL PRODUCTION ; SACCHAROMYCES-CEREVISIAE ; BIODIESEL PRODUCTION ; BAGASSE HYDROLYSATE ; ORGANIC-ACIDS ; ACETIC-ACID ; PH ; MICROORGANISMS ; INHIBITION
收录类别	SCI
语种	英语
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:000309827300073
引用统计	被引频次：13[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.giec.ac.cn/handle/344007/10585
专题	中国科学院广州能源研究所
作者单位	1.S China Univ Technol, Coll Light Ind & Food Sci, State Key Lab Pulp & Paper Engn, Guangzhou, Guangdong, Peoples R China 2.Chinese Acad Sci, Guangzhou Inst Energy Convers, Key Lab Renewable Energy & Gas Hydrate, Guangzhou, Guangdong, Peoples R China 3.S China Univ Technol, Coll Light Ind & Food Sci, Lab Appl Biocatalysis, Guangzhou, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Huang, Chao,Wu, Hong,Liu, Li-ping,et al. Effects of Alcohol Compounds on the Growth and Lipid Accumulation of Oleaginous Yeast Trichosporon fermentans[J]. PLOS ONE,2012,7(10).
APA	Huang, Chao,Wu, Hong,Liu, Li-ping,Lou, Wen-yong,&Zong, Min-hua.(2012).Effects of Alcohol Compounds on the Growth and Lipid Accumulation of Oleaginous Yeast Trichosporon fermentans.PLOS ONE,7(10).
MLA	Huang, Chao,et al."Effects of Alcohol Compounds on the Growth and Lipid Accumulation of Oleaginous Yeast Trichosporon fermentans".PLOS ONE 7.10(2012).