Lipid Biosynthesis and Metabolic Regulation in Microalgae

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	Lipid Biosynthesis and Metabolic Regulation in Microalgae
	Zhu Shunni1 ; Wang Zhongming1 ; Shang Changhua1 ; Zhou Weizheng 1,2; Yang Kang 1; Yuan Zhenhong1
	2011-10-24
发表期刊	PROGRESS IN CHEMISTRY
卷号	23 期号:10 页码:2169-2176
摘要	With the increasingly severe energy and environmental problems, biodiesel from microalgae has become a hot topic. Compared with traditional oil crops, microalgae have advantages of rapid growth, high lipid content, non-occupation of arable land, etc., which have been considered as a highly potential feedstock of biofuels. Although neutral lipids, especially triacylglycerols (TAG) which are the main feedstock of biodiesel production, can be accumulated in many algal cells under stress conditions, little is known about microalgal lipid synthesis and metabolic regulation so far. In order to better understand and manipulate microalgal lipid metabolism for improvement of lipid production, we present an overview of advances of lipid biosynthesis and metabolic regulation in microalgae, including TAG biosynthesis pathway, biochemical regulation and genetic engineering strategies. Effects of nutrition on lipid production are represented. Five genetic engineering strategies are summarized including enhancement of fatty acids synthesis pathway, enhancement of Kennedy pathway, regulation of alternative pathway of TAG, inhibition of competing pathway of lipid biosynthesis and lipid catabolism. The prospects of research on microalgal lipid metabolism are also discussed.
文章类型	Article
关键词	Microalgae Lipid Metabolism Tag Biosynthesis Biochemical Regulation Genetic Engineering
WOS标题词	Science & Technology ; Physical Sciences
研究领域[WOS]	Chemistry
关键词[WOS]	DIATOM CYCLOTELLA-CRYPTICA ; SEED OIL CONTENT ; ALGA NEOCHLORIS-OLEOABUNDANS ; GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE ; CHLAMYDOMONAS-REINHARDTII ; SILICON DEFICIENCY ; BIOFUEL PRODUCTION ; CALORIFIC VALUES ; STARCH SYNTHESIS ; OILSEED RAPE
收录类别	SCI
语种	英语
WOS类目	Chemistry, Multidisciplinary
WOS记录号	WOS:000297964900020
引用统计	被引频次：7[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.giec.ac.cn/handle/344007/10356
专题	中国科学院广州能源研究所
作者单位	1.Chinese Acad Sci, Key Lab Renewable Energy & Gas Hydrate, Guangzhou Inst Energy Convers, Guangzhou 510640, Guangdong, Peoples R China 2.S China Agr Univ, Coll Life Sci, Guangzhou 510642, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Zhu Shunni,Wang Zhongming,Shang Changhua,et al. Lipid Biosynthesis and Metabolic Regulation in Microalgae[J]. PROGRESS IN CHEMISTRY,2011,23(10):2169-2176.
APA	Zhu Shunni,Wang Zhongming,Shang Changhua,Zhou Weizheng,Yang Kang,&Yuan Zhenhong.(2011).Lipid Biosynthesis and Metabolic Regulation in Microalgae.PROGRESS IN CHEMISTRY,23(10),2169-2176.
MLA	Zhu Shunni,et al."Lipid Biosynthesis and Metabolic Regulation in Microalgae".PROGRESS IN CHEMISTRY 23.10(2011):2169-2176.