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Immobilization of Acetobacter sp CCTCC M209061 for efficient asymmetric reduction of ketones and biocatalyst recycling
Chen, Xiao-Hong1; Wang, Xiao-Ting2; Lou, Wen-Yong1,2; Li, Ying2; Wu, Hong2; Zong, Min-Hua2; Smith, Thomas J.3; Chen, Xin-De4
2012-09-04
发表期刊MICROBIAL CELL FACTORIES
卷号11
摘要

Background: The bacterium Acetobacter sp. CCTCC M209061 is a promising whole-cell biocatalyst with exclusive anti-Prelog stereoselectivity for the reduction of prochiral ketones that can be used to make valuable chiral alcohols such as (R)-4-(trimethylsilyl)-3-butyn-2-ol. Although it has promising catalytic properties, its stability and reusability are relatively poor compared to other biocatalysts. Hence, we explored various materials for immobilizing the active cells, in order to improve the operational stability of biocatalyst.

文章类型Article
关键词Immobilization Asymmetric Reduction Acetobacter Sp Cctcc M209061 Alginate-chitosan Mass Transfer
WOS标题词Science & Technology ; Life Sciences & Biomedicine
DOI10.1186/1475-2859-11-119
研究领域[WOS]Biotechnology & Applied Microbiology
关键词[WOS]ALGINATE GEL BEADS ; BAKERS-YEAST ; ENANTIOSELECTIVE REDUCTION ; DIFFUSION CHARACTERISTICS ; PROCHIRAL KETONES ; CALCIUM-ALGINATE ; IONIC LIQUID ; CHITOSAN ; CELLS ; MICROCAPSULES
收录类别SCI
语种英语
WOS类目Biotechnology & Applied Microbiology
WOS记录号WOS:000311579300001
引用统计
被引频次:42[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.giec.ac.cn/handle/344007/10194
专题中国科学院广州能源研究所
作者单位1.S China Univ Technol, State Key Lab Pulp & Paper Engn, Guangzhou 510640, Guangdong, Peoples R China
2.S China Univ Technol, Coll Light Ind & Food Sci, Lab Appl Biocatalysis, Guangzhou 510640, Guangdong, Peoples R China
3.Sheffield Hallam Univ, Biomed Res Ctr, Sheffield S1 1WB, S Yorkshire, England
4.Chinese Acad Sci, Guangzhou Inst Energy Convers, Guangzhou 510640, Guangdong, Peoples R China
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Chen, Xiao-Hong,Wang, Xiao-Ting,Lou, Wen-Yong,et al. Immobilization of Acetobacter sp CCTCC M209061 for efficient asymmetric reduction of ketones and biocatalyst recycling[J]. MICROBIAL CELL FACTORIES,2012,11.
APA Chen, Xiao-Hong.,Wang, Xiao-Ting.,Lou, Wen-Yong.,Li, Ying.,Wu, Hong.,...&Chen, Xin-De.(2012).Immobilization of Acetobacter sp CCTCC M209061 for efficient asymmetric reduction of ketones and biocatalyst recycling.MICROBIAL CELL FACTORIES,11.
MLA Chen, Xiao-Hong,et al."Immobilization of Acetobacter sp CCTCC M209061 for efficient asymmetric reduction of ketones and biocatalyst recycling".MICROBIAL CELL FACTORIES 11(2012).
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