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Immobilization of Acetobacter sp CCTCC M209061 for efficient asymmetric reduction of ketones and biocatalyst recycling
Chen, Xiao-Hong1; Wang, Xiao-Ting2; Lou, Wen-Yong1,2; Li, Ying2; Wu, Hong2; Zong, Min-Hua2; Smith, Thomas J.3; Chen, Xin-De4
2012-09-04
Source PublicationMICROBIAL CELL FACTORIES
Volume11
Abstract

Background: The bacterium Acetobacter sp. CCTCC M209061 is a promising whole-cell biocatalyst with exclusive anti-Prelog stereoselectivity for the reduction of prochiral ketones that can be used to make valuable chiral alcohols such as (R)-4-(trimethylsilyl)-3-butyn-2-ol. Although it has promising catalytic properties, its stability and reusability are relatively poor compared to other biocatalysts. Hence, we explored various materials for immobilizing the active cells, in order to improve the operational stability of biocatalyst.

SubtypeArticle
KeywordImmobilization Asymmetric Reduction Acetobacter Sp Cctcc M209061 Alginate-chitosan Mass Transfer
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
DOI10.1186/1475-2859-11-119
WOS Subject ExtendedBiotechnology & Applied Microbiology
WOS KeywordALGINATE GEL BEADS ; BAKERS-YEAST ; ENANTIOSELECTIVE REDUCTION ; DIFFUSION CHARACTERISTICS ; PROCHIRAL KETONES ; CALCIUM-ALGINATE ; IONIC LIQUID ; CHITOSAN ; CELLS ; MICROCAPSULES
Indexed BySCI
Language英语
WOS SubjectBiotechnology & Applied Microbiology
WOS IDWOS:000311579300001
Citation statistics
Cited Times:43[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.giec.ac.cn/handle/344007/10194
Collection中国科学院广州能源研究所
Affiliation1.S China Univ Technol, State Key Lab Pulp & Paper Engn, Guangzhou 510640, Guangdong, Peoples R China
2.S China Univ Technol, Coll Light Ind & Food Sci, Lab Appl Biocatalysis, Guangzhou 510640, Guangdong, Peoples R China
3.Sheffield Hallam Univ, Biomed Res Ctr, Sheffield S1 1WB, S Yorkshire, England
4.Chinese Acad Sci, Guangzhou Inst Energy Convers, Guangzhou 510640, Guangdong, Peoples R China
Recommended Citation
GB/T 7714
Chen, Xiao-Hong,Wang, Xiao-Ting,Lou, Wen-Yong,et al. Immobilization of Acetobacter sp CCTCC M209061 for efficient asymmetric reduction of ketones and biocatalyst recycling[J]. MICROBIAL CELL FACTORIES,2012,11.
APA Chen, Xiao-Hong.,Wang, Xiao-Ting.,Lou, Wen-Yong.,Li, Ying.,Wu, Hong.,...&Chen, Xin-De.(2012).Immobilization of Acetobacter sp CCTCC M209061 for efficient asymmetric reduction of ketones and biocatalyst recycling.MICROBIAL CELL FACTORIES,11.
MLA Chen, Xiao-Hong,et al."Immobilization of Acetobacter sp CCTCC M209061 for efficient asymmetric reduction of ketones and biocatalyst recycling".MICROBIAL CELL FACTORIES 11(2012).
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