Knowledge Management System Of Guangzhou Institute of Energy Conversion, CAS
In vivo detoxification of furfural during lipid production by the oleaginous yeast Trichosporon fermentans | |
Huang, Chao1,2; Wu, Hong1; Smith, Thomas J.3; Liu, Zong-jun4; Lou, Wen-Yong5; Zong, Min-hua5 | |
2012-09-01 | |
发表期刊 | BIOTECHNOLOGY LETTERS |
卷号 | 34期号:9页码:1637-1642 |
摘要 | In vivo detoxification of furfural by the oleaginous yeast, Trichosporon fermentans, under lipid-producing (i.e., nitrogen-limited) conditions was evaluated for the first time. During the initial fermentation phase, furfural was rapidly reduced to furfuryl alcohol, which is more toxic to T. fermentans than furfural. Furfuryl alcohol was subsequently oxidized to furoic acid which has low toxicity to T. fermentans and is the end product of the in vivo detoxification of furfural in this organism. These observations explain how T. fermentans can grow and accumulate lipids in medium containing furfural. They also indicate that strategies to minimize the transient production of furfuryl alcohol could further improve the capacity of the strain to produce lipids from furfural-containing lignocellulosic hydrolysates. |
文章类型 | Article |
关键词 | Detoxification Furfural Furfuryl Alcohol Furoic Acid Trichosporon Fermentans |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
DOI | 10.1007/s10529-012-0948-x |
研究领域[WOS] | Biotechnology & Applied Microbiology |
关键词[WOS] | SACCHAROMYCES-CEREVISIAE ; OIL PRODUCTION ; HYDROLYSATE ; INHIBITORS ; TOLERANCE ; GLUCOSE ; BIOMASS ; GROWTH |
收录类别 | SCI |
语种 | 英语 |
WOS类目 | Biotechnology & Applied Microbiology |
WOS记录号 | WOS:000308234400006 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.giec.ac.cn/handle/344007/10136 |
专题 | 中国科学院广州能源研究所 |
作者单位 | 1.S China Univ Technol, Coll Light Ind & Food Sci, State Key Lab Pulp & Paper Engn, Guangzhou 510640, Guangdong, Peoples R China 2.Chinese Acad Sci, Guangzhou Inst Energy Convers, Guangzhou 510640, Guangdong, Peoples R China 3.Sheffield Hallam Univ, Biomed Res Ctr, Sheffield S1 1WB, S Yorkshire, England 4.S China Univ Technol, Sch Biosci & Bioengn, Guangzhou 510640, Guangdong, Peoples R China 5.S China Univ Technol, Lab Appl Biocatalysis, Coll Light Ind & Food Sci, Guangzhou 510640, Guangdong, Peoples R China |
推荐引用方式 GB/T 7714 | Huang, Chao,Wu, Hong,Smith, Thomas J.,et al. In vivo detoxification of furfural during lipid production by the oleaginous yeast Trichosporon fermentans[J]. BIOTECHNOLOGY LETTERS,2012,34(9):1637-1642. |
APA | Huang, Chao,Wu, Hong,Smith, Thomas J.,Liu, Zong-jun,Lou, Wen-Yong,&Zong, Min-hua.(2012).In vivo detoxification of furfural during lipid production by the oleaginous yeast Trichosporon fermentans.BIOTECHNOLOGY LETTERS,34(9),1637-1642. |
MLA | Huang, Chao,et al."In vivo detoxification of furfural during lipid production by the oleaginous yeast Trichosporon fermentans".BIOTECHNOLOGY LETTERS 34.9(2012):1637-1642. |
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